Pregenetic testing

Pregenetic testing

Know genetic conditions can be detected and avoided in offspring before conception by Pregenetic Testing along with IVF

Currently, three different types of PGT exist:

PGT, or preimplantation genetic, is a genetic test performed on embryos produced through IVF. PGT gives information about embryos’ genetic health to help your care team select the best embryo for transfer and improve your chance of achieving a successful pregnancy.

How PGT Works?

PGT works by looking at the amount of genetic material within IVF embryos. This genetic material is housed within structures called chromosomes.

Embryos with the incorrect number of chromosomes (also called aneuploid embryos) typically do not result in a successful pregnancy or may lead to the birth of a child with a genetic condition.

Embryos with the correct number of chromosomes (also called euploid embryos) have a better chance of leading to a successful pregnancy.

PGT-A identifies embryos with the correct number of chromosomes, and helps to select the embryo with the best chance of leading to IVF success.

PGT-M detects the embryos with inherited genetic disorder and helps to identify the embryo most likely to result in a healthy child.

PGT-SR detects embryos with the incorrect chromosome number or structure. You may consider PGT-SR for chromosome rearrangements if you had a child or pregnancy with a chromosome rearrangement or if you or your partner are a carrier of inversion, reciprocal or robertsonian translocation

Who is PGT for?

All women are at risk of producing chromosomally abnormal embryos. Carrier screening on the intended parents (or donors) can detect if you and your partner (or the egg and sperm source) are carriers for a genetic mutation, which together can put the parent(s) at risk for an unhealthy child

 One of the benefits of opting for IVF is that patients may be tested for potential genetic problems before attempting a cycle.

Benefits of PGT?

The PGT Process

Non-invasive PGT-A (niPGT-A) is a novel approach to the genetic analysis of embryos. The premise is that the genetic material in the spent embryo culture media (SECM) corresponds to the genetic material in the embryo cells. So, in contrast to traditional PGT-A we can avoid invasive embryo biopsy to obtain DNA.
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